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| CORRESPONDENCE |
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| Year : 2013 | Volume
: 61
| Issue : 6 | Page : 703 |
Endoscopic repair of CSF rhinorrhea: Necessity of fibrin glue
Alper Nabi Erkan
Department of Otorhinolaryngology, Baskent University, Ankara, Turkey
| Date of Submission | 25-Sep-2013 |
| Date of Decision | 08-Oct-2013 |
| Date of Acceptance | 31-Dec-2013 |
| Date of Web Publication | 20-Jan-2014 |
Correspondence Address:
Alper Nabi Erkan
Department of Otorhinolaryngology, Baskent University, Ankara
Turkey
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/0028-3886.125425
How to cite this article:
Erkan AN. Endoscopic repair of CSF rhinorrhea: Necessity of fibrin glue. Neurol India 2013;61:703 |
Sir
We read the article tittled "Endoscopic repair of cerebrospinal fluid (CSF) rhinorrhea: Necessity of fibrin glue" by Mohindra et al. [1] in your journal. Before all else we thank them to cite our article. [2] In our clinical research, at first we tried to detect the effects of fibrin glue on nasal septal tissues in nasal septal deviation operations. We did not practice in CSF leak operations. The two operations are different. We did the resarch on rabbits, not on human. Our results demonstrated that fibrin glue causes distinctive inflammation, creates mucosal damage, increases mucosal thickness, decreases perichondrial thickness and cartilaginous thickness, and causes segmental cartilage loss in rabbits but we do not say anything about the effects of fibrin glue on human according to our investigation. Habesoglu et al. [3] researched the effects of fibrin glue in septal deviation operations on human and they did not report any side effects. In addition to this, they reported that fibrin glue promotes the regeneration of mucociliary activity of the injured mucosa postoperatively. According to our oppinion, further comparative clinical investigations are required to assess the clinical efficacy of fibrin glue in CSF leak operations and Mohindra and his colleaques' [1] research will serve as the basis for new investigations.
| » References | |  |
| 1. | Mohindra S, Mohindra S, Gupta K. Endoscopic repair of CSF rhinorrhea: Necessity of fibrin glue. Neurol India 2013;61:396-9. 
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| 2. | Erkan AN, Cakmak O, Kocer NE, Yýlmaz I. Effects of fibrin glue on nasal septal tissues. Laryngoscope 2007;117:491-6.
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| 3. | Habesoglu TE, Kulekci S, Habesoglu M, Deveci I, Deveci S, Toros S, et al. Comparative outcomes of using fibrin glue in septoplasty and its effect on mucociliary activity. Otolaryngol Head Neck Surg 2010;142:394-9.
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