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| AUTHORS REPLY |
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| Year : 2013 | Volume
: 61
| Issue : 6 | Page : 703 |
Authors reply
Satyawati Mohindra1, Sandeep Mohindra2, Karan Gupta1
1 Department of Otolaryngology and Head and Neck Surgery, Postgraduate Institute of Medical Education and Research, Chandigarh, India
2 Department of Neurosurgery, Postgraduate Institute of Medical Education and Research, Chandigarh, India
| Date of Web Publication | 20-Jan-2014 |
Correspondence Address:
Satyawati Mohindra
Department of Otolaryngology and Head and Neck Surgery, Postgraduate Institute of Medical Education and Research, Chandigarh
India
 Source of Support: None, Conflict of Interest: None  | Check |
How to cite this article:
Mohindra S, Mohindra S, Gupta K. Authors reply. Neurol India 2013;61:703 |
Sir
First of all we would like to thank Erkan et al.,[1] for reading our paper in detail. We have gone through their comments carefully. [2] In our study, [3] we have mentioned about their article in relation to histopathological changes which took place after application of fibrin glue. Though our study was based on pediatric population, nowhere we have mentioned that these changes were observed in human beings. Observation of these changes in human beings are difficult due to ethical considerations. In our department, [3],[4] we have been performing endoscopic closure of cerebrospinal fluid rhinorrhea with and without fibrin glue for the past many years and we have not observed any such adverse reactions like mucosal damage, increased mucosal thickness, decreased perichondrial thickness and cartilaginous thickness, and segmental cartilage loss. In our study, the rate of recurrent csf rhinorrhea in patients where fibrin glue was used, was marginally more than the non-glue group but the results were not statistically significant. As far as mentioning your article in relation to csf rhinorrhea is concerned, we do regret that, but we would like to draw your attention to your article where in introduction (first paragraph) you have mentioned the use of fibrin glue for various surgeries including csf rhinorrhea. The source of this observation has not been mentioned. Admittedly, we have presented a small series of patients and a larger series of patients and a systematically planned case-control study is required to definitely address the questions which are still remaining.
| » References | |  |
| 1. | Erkan AN, Cakmak O, Kocer NE, Yýlmaz I. Effects of fibrin glue on nasal septal tissues. Laryngoscope 2007;117:491-6. 
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| 2. | Erkan AN. Comment on "Susceptibility-weighted imaging: The value in cerebral astrocytomas" Neurol India 2014 [In this issue].
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| 3. | Mohindra S, Mohindra S, Gupta K. Endoscopic repair of CSF rhinorrhea: Necessity of fibrin glue. Neurol India 2013;61:396-9.
[PUBMED]  |
| 4. | Yadav JS, Mohindra S, Francis AA. CSF rhinorrhea-feasibility of conservative management in children. Int J Pediatr Otorhinolaryngol 2011;75:186-9.
[PUBMED] |
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