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CORRESPONDENCE |
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Year : 2014 | Volume
: 62
| Issue : 3 | Page : 343-344 |
Authors reply
N Manoj, A Arivazhagan, A Mahadevan, DI Bhat, HR Arvinda, BI Devi, S Sampath, BA Chandramouli
Department of Neurosurgery, National Institute of Mental Health and Neurosciences, Bengaluru, Karnataka, India
Date of Web Publication | 18-Jul-2014 |
Correspondence Address: A Arivazhagan Department of Neurosurgery, National Institute of Mental Health and Neurosciences, Bengaluru, Karnataka India
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/0028-3886.137034
How to cite this article: Manoj N, Arivazhagan A, Mahadevan A, Bhat D I, Arvinda H R, Devi B I, Sampath S, Chandramouli B A. Authors reply. Neurol India 2014;62:343-4 |
Sir,
We appreciate the reader for the thoughtful comments. We agree with the reader that the word incidence may not be appropriate in the strictest sense, as incidence of the disease in general population, as mentioned by the reader, is beyond the scope of the study.
However, we would like to point out that the article describes the number of new cases of lymphoma which were diagnosed by biopsy in a year. The data has been expressed as a percentage of lymphoma cases compared to all the tumors diagnosed in a fixed time frame. [1] This data would reflect the hospital based incidence of the disease as compared to prevalence, since only new cases were considered. Prevalence, as also defined by the reader, is the proportion of cases in the population at a given time rather than rate of occurrence of new cases. [2] In our study, previously diagnosed and pre- existing cases in a year were not considered and only newly diagnosed cases were considered, and therefore the data does not reflect prevalence. We agree that the data may not reflect the hospital based incidence in the strictest sense since the denominator is not formed by all the tumor cases seen in a year. Only number of tumor biopsies formed the denominator. Therefore, the "proportion of lymphomas among all the biopsies in a year" could be a better representation of the data described in the study. [2]
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1. | Manoj N, Arivazhagan A, Mahadevan A, Bhat DI, Arvinda HR, Devi BI, et al. Central nervous system lymphoma: Patterns of incidence in Indian population and effect of steroids on stereotactic biopsy yield. Neurol India 2014;62:19-25.  [PUBMED] |
2. | Principles of epidemiology and epidemiologic methods. In: Park K, editor. Park′s Textbook of Preventive and Social Medicine. 22 nd ed. Jabalpur: Banarsidas Bhanot Publishers. 2013. p. 50-126.  |
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