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Table of Contents    
Year : 2014  |  Volume : 62  |  Issue : 4  |  Page : 483-484

Clinical Practice of Multiple Sclerosis

Department of Neurology, Medical College, Kottayam, Kerala, India

Date of Web Publication19-Sep-2014

Correspondence Address:
M Madhusudanan
Department of Neurology, Medical College, Kottayam, Kerala
M Madhusudanan
Department of Neurology, Medical College, Kottayam, Kerala
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0028-3886.141306

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How to cite this article:
Madhusudanan M, Madhusudanan M. Clinical Practice of Multiple Sclerosis. Neurol India 2014;62:483-4

How to cite this URL:
Madhusudanan M, Madhusudanan M. Clinical Practice of Multiple Sclerosis. Neurol India [serial online] 2014 [cited 2020 Oct 23];62:483-4. Available from:

Editors: M.V. Padma Srivastva and Rohit Bhatia

Publisher: Kontentwork a division of KWX Communication Pvt. Ltd, New Delhi, India

ISBN: 978-81-926567-0-0

Over the last 15 years, in India, interest in multiple sclerosis (MS) has increased probably more than for any other neurologic disorder. This arises from the simultaneous availability of magnetic resonance imaging (MRI) technology that has permitted clinicians to image the pathologic process and the development of therapeutic agents that have brought hope to patients. These facts have sparkled interests in the minds of Indian neurologists and many new cases andatypical cases are described from all over the country. Under the circumstances, the book on "CLINICAL PRACTICE OF MULTIPLE SCLEROSIS, edited by Padma Srivastava and Rohit Bhatia is a wonderful hand book for practicing neurologists in the country, which contains latest evidence-based approach in both the clinical diagnosis and managementof multiple sclerosis. The chapters in the book are written by the authorities in this field including Professor Bhim Singal who have done pioneering work in this field in India.

This book provides a comprehensive and state of the art overview of MS. The chapters emphasize current criteria for diagnosis andincorporate the rapidly developing strategies in the diagnosis and management. The chapters are comprehensive and authoritative. Throughout the text book, the authors have thoughtfully included case vignettes and very useful and comprehensive charts and tables which makes this book unique in its own right. The purpose is to provide a clinically inspired but scientifically guided approach to diagnosis and management of MS. Themost attracting thing in this review was that the authors have critically evaluated the pitfalls in using the recent criteria for diagnosis of MS and highlighted the problems in blindly applying the management protocols of MS proposed for Caucasian population to Indian population taking into consideration the differences in clinical presentation and natural history. The chapters on "Initiating therapy in MS" and "Drug therapy for relapsing and remitting multiple sclerosis" have particularly attracted me and contain very useful information for the practising neurologists. The chapter on management of MS balances its emphasis on pharmacologic as well as non-pharmacologic approach to the treatment and gives advice regarding the cognitive, behavioral and physical components of treatment.

The authors have aptly discussed the appearanceof early axonal pathology and the imaging techniques capable of identifying and quantifying brain atrophy and its relevance in the progressive phase of MS. The authors have discussed the merits and demerits of oral preparations which are being developed based on a detailed understanding of the immune process. I wish the authors should consider a chapter on the "pathophysiology of MS and mechanism of action of the various Disease modifying drugs" in their next edition.

Over all this book has number of strengths including excellent author selection, practical clinical approach to the problems, good use of tables summarizing the essentials and evidence based management quoting land mark studies in the treatment of MS.

I highly recommend this work to any practicing neurologist who handle multiple sclerosis cases in their clinic.


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Online since 20th March '04
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