| ORIGINAL ARTICLE |
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| Year : 2015 | Volume
: 63
| Issue : 1 | Page : 30--34 |
Series of paraneoplastic vasculitic neuropathy: A rare, potentially treatable neuropathy
Meena A Kannan1, Sundaram Challa2, Rukmini M Kandadai1, Megha S Uppin2, Sheik A Jabeen1, Rupam Borgohain1
1 Department of Neurology, Nizam's Institute of Medical Sciences, Punjagutta, Hyderabad, Telangana, India
2 Department of Pathology, Nizam's Institute of Medical Sciences, Punjagutta, Hyderabad, Telangana, India
Correspondence Address:
Dr. Meena A Kannan
Department of Neurology, Nizam's Institute of Medical Sciences, Punjagutta, Hyderabad - 500 082, Telangana
India
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/0028-3886.152629
Background: Paraneoplastic vasculitic neuropathy (PVN) is a rare paraneoplastic syndrome. It is characterized by non-systemic subacute vasculitic neuropathy. It is most commonly associated with small cell lung cancers (SCLC) and lymphomas. PVN presents as a painful symmetrical or asymmetrical sensorimotor axonal neuropathy. The neurological symptoms may predate the tumor and may be the initial manifestations, or they may develop after a tumor is diagnosed. Recognition of this entity is important because of its potential treatability.
Aim: To study the clinical features of PVN and briefly review the literature.
Materials and Methods: The data was collected retrospectively from the medical records of our hospital.
Results: Of the 14 cases of paraneoplastic neuropathies, 4 had a PVN. The age of onset was more than 50 years and there was no sex preponderance. Pain was seen in three patients. Two patients were previously treated for a thymoma. Two patients, following their presentation with PVN, were diagnosed with a colonic carcinoma and lung carcinoma, respectively.
Conclusions: The recognition of PVN is important as this syndrome may respond to immunosuppression and tumor removal.
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