| REVIEW ARTICLE |
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| Year : 2017 | Volume
: 65
| Issue : 7 | Page : 71--77 |
From resection to ablation: A review of resective surgical options for temporal lobe epilepsy and rationale for an ablation-based approach
Anne Coyle, Jonathan Riley, Chengyuan Wu, Ashwini Sharan
Department of Neurosurgery, Thomas Jefferson University, Philadelphia, Pennsylvania, USA
Correspondence Address:
Ashwini Sharan
Department of Neurosurgery, Thomas Jefferson University, 909 Walnut Street, 3rd Floor, Philadelphia, Pennsylvania
USA
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/0028-3886.201662
Surgical intervention is of proven benefit in an appropriately selected subset of patients with medically refractory temporal lobe epilepsy. In these patients, a surgical cure both provides the quality of life improvement that comes from seizure freedom as well as a survival benefit. However, patients who undergo open surgical intervention may have a worsening in neurobehavioral outcomes. Laser interstitial thermal therapy (LITT) represents a minimally invasive surgical intervention that has shown promise in improving post-operative neurobehavioral outcomes. Further, the minimally invasive nature of this procedure holds the possibility to shift the significant under-penetration of surgical intervention that exists for eligible medically refractory patients. Herein, we review open surgical resection-based techniques and the clinical data to date for LITT.
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