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|Year : 2019 | Volume
| Issue : 4 | Page : 1168
Malgorzata Blauciak1, Joanna Bladowska2, Boguslaw Paradowski1
1 Department of Clinical Neurology, Wroclaw Medical University, Wroclaw, Poland
2 Departments of General Radiology, Interventional Radiology and Neuroradiology, Wroclaw Medical University, Wroclaw, Poland
|Date of Web Publication||10-Sep-2019|
Dr. Malgorzata Blauciak
University Hospital in Wroclaw, Ulica Borowska 213, Wroclaw 50-556
Source of Support: None, Conflict of Interest: None
|How to cite this article:|
Blauciak M, Bladowska J, Paradowski B. Susac's Syndrome. Neurol India 2019;67:1168
A 21-year-old woman was admitted to the hospital with symptoms of headache, nausea, and bilateral hearing loss without any vision impairment. She also showed cerebrospinal fluid lymphocytic pleocytosis, elevated protein, and oligoclonal bands are characteristic of autoimmune processes. Magnetic resonance imaging examination revealed multiple hyperintense lesions in the central part of the corpus callosum as well as in the posterior limb of internal capsule (PLIC) presenting as a typical string-of-pearls sign on T2-weighted images [Figure 1]. A diagnosis of Susac's syndrome was made and treatment with pulses of methylprednisolone was administered. Susac's syndrome is a rare autoimmunological inflammation of the small arterial vessels. Only 13% of patients present with the classical triad of symptoms (encephalopathy, hearing loss, and branch retinal artery occlusions).
|Figure 1: Magnetic resonance examination, T2-weighted images. Multiple hyperintense lesions involving corpus callosum (a) as well as PLIC (b) are visible. The lesions are typically located in the central part of the corpus callosum and they show the so-called string-of-pearls sign in PLIC|
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Małgorzata Błauciak - concept and design, acquisition of data, analysis and interpretation of data critical revision of the manuscript for intellectual content, final approval of the version to be published.
Joanna Bladowska – concept and design, acquisition of data, analysis and interpretation of data critical revision of the manuscript for intellectual content, final approval of the version to be published.
Bogusław Paradowski – concept and design, acquisition of data, analysis and interpretation of data critical revision of the manuscript for intellectual content, final approval of the version to be published.
Declaration of patient consent
The authors certify that they have obtained all appropriate patient consent forms. In the form the patient(s) has/have given his/her/their consent for his/her/their images and other clinical information to be reported in the journal. The patients understand that their names and initials will not be published and due efforts will be made to conceal their identity, but anonymity cannot be guaranteed.
Financial support and sponsorship
Conflicts of interest
There are no conflicts of interest.
| » References|| |
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Kleffner I, Dorr J, Ringelstein M, Gross C, Böckenfeld Y, Schwindt W, et al
. Diagnostric criteria for Susac syndrome. J Neurol Neurosurg Psychiatry 2016;87:1287-95.