| REVIEW ARTICLE |
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| Year : 2019 | Volume
: 67
| Issue : 7 | Page : 32--37 |
Treatment of neuropathic pain after peripheral nerve and brachial plexus traumatic injury
Ana Carolina Lovaglio, Mariano Socolovsky, Gilda Di Masi, Gonzalo Bonilla
Peripheral Nerve and Plexus Program, Department of Neurosurgery, University of Buenos Aires School of Medicine, Buenos Aires, Argentina
Correspondence Address:
Dr. Ana Carolina Lovaglio
Peripheral Nerve and Plexus Program, Department of Neurosurgery, University of Buenos Aires School of Medicine, Buenos Aires
Argentina
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/0028-3886.250699
Peripheral nerve and brachial plexus injuries typically cause severe impairment in the affected limb. The incidence of neuropathic pain is high, reaching up to 95% of cases, especially if cervical root avulsion has occurred. Neuropathic pain results from damage to the somatosensory system, and its progression towards chronicity depends upon disruptions affecting both the peripheral and central nervous system. Managing these painful conditions is complex and must be accomplished by a multidisciplinary team, starting with first-line pharmacological therapies like tricyclic antidepressants and calcium channel ligands, combined physical and occupational therapy, transcutaneous electrical stimulation and psychological support. For patients refractory to the initial measures, several neurosurgical options are available, including nerve decompression or reconstruction and ablative/modulatory procedures.
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