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Table of Contents    
Year : 2020  |  Volume : 68  |  Issue : 3  |  Page : 701

Comments on “Sternberg's Canal—A Rare Cause of Spontaneous Cerebrospinal Fluid Rhinorrhea”

Department of Otolaryngology, Head and Neck Surgery, University of Alabama at Birmingham, Birmingham, AL, United States of America

Date of Web Publication6-Jul-2020

Correspondence Address:
Bradford A Woodworth
UAB - Department of Otolaryngology, FOT 1155,1720 2nd Avenue S, Birmingham, AL 35294-3412
United States of America
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0028-3886.289009

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How to cite this article:
Thompson HM, Woodworth BA. Comments on “Sternberg's Canal—A Rare Cause of Spontaneous Cerebrospinal Fluid Rhinorrhea”. Neurol India 2020;68:701

How to cite this URL:
Thompson HM, Woodworth BA. Comments on “Sternberg's Canal—A Rare Cause of Spontaneous Cerebrospinal Fluid Rhinorrhea”. Neurol India [serial online] 2020 [cited 2023 Oct 2];68:701. Available from:


A recent article by Jayaprakash et al., “Sternberg's canal—A rare cause of spontaneous cerebrospinal fluid rhinorrhea”, presents a case of spontaneous cerebrospinal fluid (CSF) rhinorrhea that the authors determine to be linked to Sternberg's canal.[1] The association of lateral sphenoid recess CSF leaks to the persistence of this canal is an assertion that is inconsistent with the original description of this congenital canal.

The article states that the leak was determined to be in the inferolateral wall of the right sphenoid sinus. Sternberg originally described a congenital persistence secondary to failure of fusion of multiple sphenoid ossification centers which form a canal that runs entirely medial to the superior orbital fissure. For this reason, a CSF leak lateral to this landmark cannot be attributed to Sternberg's canal.[2] The vast majority of lateral sphenoid CSF leaks (as in the current case) occur lateral to the infraorbital nerve and foramen rotundum.

It is far more likely that there is another etiologic, non-congenital origin to lateral sphenoid recess leaks such as idiopathic intracranial hypertension (IIH). In 2014, Illing et al. showed that of 77 lateral recess of the sphenoid (LRS) CSF leaks, 96% were associated with radiographic findings of intracranial hypertension, such as empty sella and arachnoid pits, and 95% were associated with elevated opening pressure on lumbar drain or ventriculostomy pressure measurements.[3] The patient described in the article is a 37-year-old female, but no body mass index is mentioned. It is highly likely this patient has undiagnosed IIH that led to arachnoid pits in the lateral sphenoid roof and herniation of the brain through the defect. This patient should be followed long term and possibly see a neuroopthalmologist for evaluation.[4] She is more likely to have a recurrence since no pressure lowering measures were provided.[5]

We encourage the authors of the manuscript to read the original descriptions and treatise regarding Sternberg's canal. The mention of a “congenital” cause of LRS defects attributable to this canal should be eradicated from the literature.


Bradford A. Woodworth, MD is a consultant for Cook Medical, Baxter, and Smith and Nephew.

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Conflicts of interest

There are no conflicts of interest.

 » References Top

Jayaprakash N, Kumar RR, Devanand B, Vaishnavi VA. Sternberg's canal-A rare cause of spontaneous cerebrospinal fluid rhinorrhea. Neurol India 2017;65:1429-30.  Back to cited text no. 1
[PUBMED]  [Full text]  
Baranano CF, Cure J, Palmer JN, Woodworth BA. Sternberg's canal: Fact or fiction? Am J Rhinol Allergy 2009;23:167-71.  Back to cited text no. 2
Illing E, Schlosser RJ, Palmer JN, Cure J, Fox N, Woodworth BA. Spontaneous sphenoid lateral recess cerebrospinal fluid leaks arise from intracranial hypertension, not Sternberg's canal. Int Forum Allergy Rhinol 2014;4:246-50.  Back to cited text no. 3
Aaron G, Doyle J, Vaphiades MS, Riley KO, Woodworth BA. Increased intracranial pressure in spontaneous CSF leak patients is not associated with papilledema. Otolaryngol Head Neck Surg 2014;151:1061-6.  Back to cited text no. 4
Teachey W, Grayson J, Cho DY, Riley KO, Woodworth BA. Intervention for elevated intracranial pressure improves success rate after repair of spontaneous cerebrospinal fluid leaks. Laryngoscope 2017;127:2011-6.  Back to cited text no. 5

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