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NI FEATURE: THE FIRST IMPRESSION |
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Year : 2020 | Volume
: 68
| Issue : 5 | Page : 971 |
The Cover Page – DREZOTOMY
Sandeep Kandregula, Bharat Guthikonda
Department of Neurosurgery, LSU Health Sciences, Shreveport, LA 71103
Date of Web Publication | 27-Oct-2020 |
Correspondence Address: Sandeep Kandregula Department of Neurosurgery, LSU Health Sciences, Shreveport, LA 71103
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/0028-3886.299143
How to cite this article: Kandregula S, Guthikonda B. The Cover Page – DREZOTOMY. Neurol India 2020;68:971 |
DREZotomy is a procedure that destroys the dorsal root entry zone and thereby providing pain relief by blocking the pain pathway in selected spinal cord segments. Sindou, et al. initially described this for a patient with a Pancoast tumor invading the brachial plexus.[1] Since then, the procedure was modified and applied. This ablation can be achieved through multiple methods like bipolar coagulation, radiofrequency/laser ablation, micro scissors[2]/surgical scalpel, and ultrasonic ablation. The literature reports that DREZotomy is more successful in patients with brachial plexus avulsion injuries.[1],[3] The principle behind all these procedures is to destroy the affected spinal cord segments' dorsal root entry zone. Newer treatment methods include modulating the dorsal root ganglion through the DRG stimulator without destroying the dorsal root entry zone.[4]
Long term results of DREZotomy showed to achieve adequate pain control in 88% of patients suffering from predominant paroxysmal pain and 20% in continuous pain[5]. In this illustration, we intend to show different methods to ablate the dorsal root entry zone, to alleviate the pain.

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1. | Sindou MP, Blondet E, Emery E, Mertens P. Microsurgical lesioning in the dorsal root entry zone for pain due to brachial plexus avulsion: A prospective series of 55 patients. J Neurosurg2005;102:1018-8. |
2. | Agrawal D, Garg K. Microscissor DREZotomy - A New Way for 'Atraumatic Lesioning' of DREZ. Neurol India 2019;67:1320-2. |
3. | Baruah S, Devi BI, Bhat DI, Shukla D. Drezotomy in the management of post brachial plexus injury neuropathic pain: Preliminary results. The Indian Journal of Neurotrauma2014;11:27-9. |
4. | Harrison C, Epton S, Bojanic S, Green AL, FitzGerald JJ. The Efficacy and Safety of Dorsal Root Ganglion Stimulation as a Treatment for Neuropathic Pain: A Literature Review. Neuromodulation2018;21:225-33. |
5. | Sindou M, Mertens P, Wael M. Microsurgical DREZotomy for pain due to spinal cord and/or cauda equina injuries: Long-term results in a series of 44 patients. Pain2001;92:159-71. |
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