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Year : 2020  |  Volume : 68  |  Issue : 6  |  Page : 1469--1471

A Case of Pregabalin-Induced Parkinsonism

1 University of Health Sciences, Erenkoy Mental Health and Neurological Disorders Research and Training Hospital, Neurology Department, Istanbul-, Turkey
2 Bahcesehir University Medical Faculty, Neurology Department, Istanbul –, Turkey

Correspondence Address:
Dr. Buse Cagla ARI
Erenkoy Ruh ve Sinir Egitim ve Arastirma Hastanesi Noroloji Yatan Hasta Servisi Sinan Ercan Cad. No: 29 34744 Kazasker – Kadikoy/Istanbul
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0028-3886.304071

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Drug-induced parkinsonism is the second common movement disorder after Parkinson's disease. It occurs due to the use of not only neuroleptics but also some other medications as pregabalin. Pregabalin is an antiepileptic drug and a structural analog of gamma-aminobutyric acid (GABA), and its use decreases the release of several neurotransmitters. In this case report, we present a 53-year-old female patient with the signs of parkinsonism following pregabalin treatment. Drug-induced parkinsonism was diagnosed based on the clinical features, investigations, and resolution of the complaints. The symptoms relieved after the treatment stopped at a follow-up of 10 days. Due to the rare report of pregabalin-induced parkinsonism, we aim to enhance clinicians' awareness of pregabalin's probable side effects.


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Online since 20th March '04
Published by Wolters Kluwer - Medknow