REVIEW ARTICLE |
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Year : 2020 | Volume
: 68
| Issue : 7 | Page : 129--133 |
Modern Methods of Stereotactic Radiosurgery and Radiotherapy for the Treatment of Cushing Disease
Ashraf Abdali1, Ludmila Astaf`eva1, Yuriy Trunin1, Pavel Kalinin1, Andrey Golanov1, Badshahzar Abdali2, Gennady Chmutin1, Alexey Shkarubo1, Bipin Chaurasia2
1 N.N. Burdenko National Medical Research Center of Neurosurgery; Department of Neurological Diseases and Neurosurgery, Peoples' Friendship University of Russia, Moscow, Russian Federation 2 Department of Neurological Diseases and Neurosurgery, Peoples' Friendship University of Russia, Moscow, Russian Federation
Correspondence Address:
Dr. Ashraf Abdali 4th Tverskaya Yamskaya 16, Moscow Russia 125047. 8th, Neurosurgical Department of Skull Base Basal Tumors Russian Federation
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/0028-3886.287663
Cushing's disease is caused by a pituitary tumor causing increased production of adrenocorticotropic hormone, which leads to chronic hypersecretion of cortisol through adrenal cortices. Endoscopic trans-sphenoidal adenomectomy is the first choice of treatment with greatest efficiency for the treatment of the disease. However, in the absence of remission or recurrence of hypercortisolism after neurosurgical resection (adenomectomy), as well as in cases when surgical intervention cannot be carried due to medical contraindications to surgical intervention, radiation treatment is used as an alternative or adjoining therapy. In this literature review the efficiency of different radiation techniques (the conventional and the modern techniques), as well as possible complications of modern methods of radiosurgery and radiotherapy have been looked for.
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