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Year : 2020  |  Volume : 68  |  Issue : 8  |  Page : 170--178

Neuromodulation Options and Patient Selection for Parkinson's Disease

1 Department of Neurology, All India Institute of Medical Sciences, New Delhi, India
2 Department of Neurology, P. J. Safarik University; Department of Neurology, University Hospital of L. Pasteur, Kosice, Slovakia, USA
3 Department of Neurology, University of Missouri-School of Medicine, Columbia, MO, USA
4 Department of Neurology, National Neuroscience Institute, King Fahad Medical City, Riyadh, Saudi Arabia
5 Department of Neurosurgery, National Neuroscience Institute, King Fahad Medical City, Riyadh, Saudi Arabia
6 Department of Neurological Surgery, West Virginia University, Morgantown, WV, USA

Correspondence Address:
Dr. Jawad A Bajwa
Department of Neurology, National Neuroscience Institute, King Fahad Medical City, As Sulimaniyah, Riyadh – 12231
Saudi Arabia
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0028-3886.302473

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Neuromodulation therapies, including deep brain stimulation (DBS) and pump therapies, are currently the standard of care for PD patients with advanced disease and motor complications that are difficult to control with medical management alone. The quest for alternate lesser invasive approaches led to the development of several novel therapies like intrajejunal levodopa infusions (IJLI), continuous subcutaneous apomorphine infusions (CSAI) and Magnetic Resonance guided Focused Ultrasound (MRgFUS) in recent years. To achieve good outcomes with any of these therapeutic modalities, careful patient selection, multidisciplinary evaluation and technical expertise are equally important. In this review, we will provide an overview of the neuromodulation strategies currently available for PD, emphasizing on patient selection and choosing among the various strategies.


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Online since 20th March '04
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