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Year : 2020  |  Volume : 68  |  Issue : 8  |  Page : 249--258

Role of Neuromodulation for Treatment of Drug-Resistant Epilepsy

1 Department of Neurology, Lady Harding Medical College, New Delhi, India
2 Department of Neurosurgery, AIIMS, New Delhi, India
3 Department of Neurology, AIIMS, New Delhi, India

Correspondence Address:
Dr. Manjari Tripathi
Professor, Department of Neurology, Room 705, 7th Floor, CN Center, AIIMS, New Delhi - 110 029
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0028-3886.302476

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The choice of neuromodulation techniques has greatly increased over the past two decades. While vagal nerve stimulation (VNS) has become established, newer variations of VNS have been introduced. Following the SANTE's trial, deep brain stimulation (DBS) is now approved for clinical use. In addition, responsive neurostimulation (RNS) has provided exciting new opportunities for treatment of drug-resistant epilepsy. While neuromodulation mostly offers only a ‘palliative’ measure, it still provides a significant reduction of frequency and intensity of epilepsy. We provide an overview of all the techniques of neuromodulation which are available, along with long-term outcomes. Further research is required to delineate the exact mechanism of action, the indications and the stimulation parameters to extract the maximum clinical benefit from these techniques.


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Online since 20th March '04
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