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 CASE REPORT
Year : 2021  |  Volume : 69  |  Issue : 2  |  Page : 493--494

An Unusual Case of Muscle Twitching: Its LGI1


Department of Neurology, Sir Ganga Ram Hospital, Old Rajendra Nagar, New Delhi, India

Correspondence Address:
Dhrumil Jatinbhai Shah
Department of Neurology, Sir Ganga Ram Hospital, Old Rajendra Nagar, New Delhi - 110 060
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0028-3886.314549

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A 50-year-old male, presented with a two-months history of ascending paresthesias, with continuous twitchings over the body, associated with insomnia. His electromyography (EMG) revealed neuromyotonia and was diagnosed as a case of peripheral nerve hyperexcitability (PNH) syndrome due to Leucin-rich glioma-inactivated 1 (LGI1) antibody. He showed significant improvement with intravenous immunoglobulin and carbamazepine.






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