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Year : 2021  |  Volume : 69  |  Issue : 5  |  Page : 1402--1404

Isolated Enhancement Effect is the Only MRI Finding for Wernicke's encephalopathy

1 Department of Neurology, Zhengzhou University People's Hospital, Zhengzhou, Henan, China
2 Department of Neurology, The Second Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China

Correspondence Address:
Jie-Wen Zhang
Department of Neurology, Zhengzhou University People's Hospital, Zhengzhou, Henan - 450003
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0028-3886.329531

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Wernicke's encephalopathy (WE) is an acute neuropsychiatric disorder that results from thiamine (vitamin B1) deficiency. The typical clinical manifestations, which occur as triads in 20% of patients with the disorder, are acute mental status changes, ophthalmoplegia, and ataxia. Brain magnetic resonance imaging (MRI) has important value in diagnosis as it can reveal abnormalities in the thalamus, mammillary body, third and fourth ventricles, and periaqueductal area. Here we describe a 44-year-old female patient with WE, in the context of fasting following bowel surgery. The unique neuroimaging findings were symmetrical mammillary body and dorsal midbrain abnormalities, only evident on contrast-enhanced brain MRI.


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Online since 20th March '04
Published by Wolters Kluwer - Medknow