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Year : 1998  |  Volume : 46  |  Issue : 2  |  Page : 102--104

Gabapentin in refractory partial seizures.

M Dhanaraj, CU Velmurugendran 
 Department of Neurology, Govt. General Hospital, Madras - 600 003, India

Correspondence Address:
M Dhanaraj
Department of Neurology, Govt. General Hospital, Madras - 600 003
India

We report our preliminary observations on the role of Gabapentin as an add - on therapy in 16 patients with partial or secondary generalised seizures who were resistant to conventional antiepileptic drugs. There was a reduction in the seizure frequency by more than 50 in 11 (69), less than 50 in 3 (18.75), and increase in 1 (6.25). Adverse effects were noted in 9 (56.25 ) of them. The giddiness and sleepiness was seen in 5 (31.25 ); in one it was so severe that he withdrew from the study. Ataxic gait was observed in 1 (6.25). Reduction in the haemoglobin by 2 gms. occurred in 2 (12.5) and asymptomatic eosinophilia in 1 (6.25). As an add - on drug, the efficacy of Gabapentin was good. Regular haematological monitoring is necessary while the patients are on the drug. Further studies involving large number of patients in our country is necessary.


How to cite this article:
Dhanaraj M, Velmurugendran C. Gabapentin in refractory partial seizures. Neurol India 1998;46:102-104


How to cite this URL:
Dhanaraj M, Velmurugendran C. Gabapentin in refractory partial seizures. Neurol India [serial online] 1998 [cited 2021 Jan 15 ];46:102-104
Available from: https://www.neurologyindia.com/article.asp?issn=0028-3886;year=1998;volume=46;issue=2;spage=102;epage=104;aulast=Dhanaraj;type=0