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ORIGINAL ARTICLE
Year : 2004  |  Volume : 52  |  Issue : 1  |  Page : 79--81

Cerebral blood flow velocity changes under nitrous oxide halothane anesthesia in patients with frontotemporal gliomas: A comparison of the normal and abnormal cerebral hemispheres

GV Vajramuni1, GS Umamaheswara Rao2, SV Pillai2 
1 J. N. Medical College, Belgaum, India
2 National Institute of Mental Health and Neurosciences, Bangalore - 560029, India

Correspondence Address:
G S Umamaheswara Rao
National Institute of Mental Health and Neurosciences, Bangalore - 560029
India

Background: Regional differences in vascular response to anesthetic agents in brain areas with and without tumors have not been investigated till now. The existence of such differences may influence the regional distribution of cerebral blood flow under anesthesia. Material and Methods: In 8 patients with frontotemporal gliomas, middle cerebral artery blood flow velocity (Vmca), pulsatality index (PI) and resistance index (RI) were determined in the normal and pathological cerebral hemispheres before and after stable nitrous oxide-halothane anesthesia. Results: During halothane anesthesia, there was an increase in Vmca both in the normal cerebral hemisphere (69 11 to 100 38 cm/s; P = 0.05) and the hemisphere with tumor (65 17 to 83 28 cm/s; P = 0.04). A significant decrease in the pulsatality index and the resistance index was also observed in both the hemispheres (P < 0.05). The percentage changes of Vmca,, PI and RI in both the hemispheres after anesthesia were not significantly different. Conclusions: In patients with cerebral tumors, nitrous oxide-halothane anesthesia causes comparable changes of cerebral blood flow velocities in the hemisphere with tumor and the normal hemisphere.


How to cite this article:
Vajramuni G V, Umamaheswara Rao G S, Pillai S V. Cerebral blood flow velocity changes under nitrous oxide halothane anesthesia in patients with frontotemporal gliomas: A comparison of the normal and abnormal cerebral hemispheres.Neurol India 2004;52:79-81


How to cite this URL:
Vajramuni G V, Umamaheswara Rao G S, Pillai S V. Cerebral blood flow velocity changes under nitrous oxide halothane anesthesia in patients with frontotemporal gliomas: A comparison of the normal and abnormal cerebral hemispheres. Neurol India [serial online] 2004 [cited 2021 Jul 26 ];52:79-81
Available from: https://www.neurologyindia.com/article.asp?issn=0028-3886;year=2004;volume=52;issue=1;spage=79;epage=81;aulast=Vajramuni;type=0