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ORIGINAL ARTICLE
Year : 2004  |  Volume : 52  |  Issue : 2  |  Page : 206--209

Possible relationship between phenylthiocarbamide taste sensitivity and epilepsy

SK Pal1, K Sharma1, A Pathak2, I MS Sawhney3, S Prabhakar3 
1 Department of Anthropology, Panjab University, Chandigarh - 160014, India
2 Departments of Neurosurgery, Postgraduate Institute of Medical Education and Research, Chandigarh - 160012, India
3 Departments of Neurology, Postgraduate Institute of Medical Education and Research, Chandigarh - 160012, India

Correspondence Address:
K Sharma
Department of Anthropology, Panjab University, Chandigarh - 160014
India

The study was based on the data of a sample of 400 epileptic patients (200 idiopathic and 200 symptomatic) and 100 normal healthy individuals serving as controls. The PTC threshold distribution was bimodal. The number of non-tasters among idiopathic epileptics (35.5%) and symptomatic epileptics (32.5%) was significantly higher than controls (20%). The relative incidence of non-tasters in idiopathic and symptomatic epilepsies was 2.20 and 1.93 respectively. There is evidence that non-tasters tend to ingest a greater quantity of bitter tasting goitrogenic substances present naturally in edible plants which in turn exert greater thyroid stress in non-tasters or less sensitive tasters. Such a stress during intrauterine or early childhood growth and development might have affected neurological maturation which in turn made them more susceptible to epilepsy than tasters, who faced lesser stress.


How to cite this article:
Pal S K, Sharma K, Pathak A, Sawhney I M, Prabhakar S. Possible relationship between phenylthiocarbamide taste sensitivity and epilepsy.Neurol India 2004;52:206-209


How to cite this URL:
Pal S K, Sharma K, Pathak A, Sawhney I M, Prabhakar S. Possible relationship between phenylthiocarbamide taste sensitivity and epilepsy. Neurol India [serial online] 2004 [cited 2021 Dec 3 ];52:206-209
Available from: https://www.neurologyindia.com/article.asp?issn=0028-3886;year=2004;volume=52;issue=2;spage=206;epage=209;aulast=Pal;type=0