LETTER TO EDITOR |
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| Year : 2004 | Volume
: 52
| Issue : 2 | Page : 271- |
Satoyoshi syndrome: Comments
Boby M Varkey
Mayo Clinic , Rochester, MN, USA
Correspondence Address:
Boby M Varkey
Mayo Clinic , Rochester, MN
USA
How to cite this article:
Varkey BM. Satoyoshi syndrome: Comments.Neurol India 2004;52:271-271
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How to cite this URL:
Varkey BM. Satoyoshi syndrome: Comments. Neurol India [serial online] 2004 [cited 2021 Jan 22 ];52:271-271
Available from: https://www.neurologyindia.com/text.asp?2004/52/2/271/11068 |
Full Text
Sir,
I read with interest a case report of Satoyoshi syndrome by Ashalatha et al.[1] The similarity with a 'jerking stiff-man syndrome' -a variant of stiff-man syndrome (SMS) is striking. Distal limb involvement, myoclonic jerking, board-like muscles, stimulus-evoked spasms, endocrinopathies, vitiligo, pernicious anemia and sicca syndrome can also be seen in jerking SMS.[2] Continuous motor unit activity (CMUA) is necessary to diagnose this variant but can sometimes be elusive and manifest only in the paraspinal muscles.[3] Earlier this year, anti-GAD antibodies were described with Satoyoshi syndrome.[4] This validates the auto-immune nature of this disorder and suggests that it might be a variant of stiff-man syndrome. In both cases, a partial response to immunomodulating agents such as immuno-globulin or high dose steroids may be seen. I wonder if anti-GAD antibodies could be tested in the described case as well.
References
| 1 | Ashalatha R, Kishore A, Sarada C, Nair MD. Satayoshi syndrome. Neurol India 2004;52:94-5. |
| 2 | Meinck HM, Thompson PD. Stiff man syndrome and related conditions. Mov Disord. 2002;17:853-66. |
| 3 | Brown P, Marsden CD. The stiff man and stiff man plus syndromes.J Neurol. 1999;246:648-52. |
| 4 | Drost G, Verrips A, Hooijkaas H, Zwarts M. Glutamic acid decarboxylase antibodies in Satoyoshi syndrome. Ann Neurol. 2004;55:450-1. |
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