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Year : 2021  |  Volume : 69  |  Issue : 1  |  Page : 234--235

Fibrolipomatous Hamartoma of Median and Ulnar Nerve: A Rare Combination

Arshed H Parry, Haseeb A Wani, Feroze A Shaheen 
 Department of Radiodiagnosis, Sher-i-Kashmir Institute of Medical Sciences, Srinagar, Jammu and Kashmir, India

Correspondence Address:
Arshed H Parry
Department of Radiodiagnosis, Sher-i-Kashmir Institute of Medical Sciences, Soura, Srinagar, Jammu and Kashmir - 190 011

How to cite this article:
Parry AH, Wani HA, Shaheen FA. Fibrolipomatous Hamartoma of Median and Ulnar Nerve: A Rare Combination.Neurol India 2021;69:234-235

How to cite this URL:
Parry AH, Wani HA, Shaheen FA. Fibrolipomatous Hamartoma of Median and Ulnar Nerve: A Rare Combination. Neurol India [serial online] 2021 [cited 2021 May 6 ];69:234-235
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Full Text

A 32-year-old male presented with complaints of pain and paresthesia in the left hand, in the distribution of median and ulnar nerve, associated with gradual enlargement of swelling over the volar aspect of the wrist for the last one year. Physical examination revealed a palpable swelling on the volar aspect of wrist and hypothenar eminence. The patient felt paresthesia in the fingers upon compression of the mass.

Magnetic resonance imaging (MRI) of wrist revealed bulky and enlarged median and ulnar nerves with fat bundles interspersed between the thickened axonal bundles with thick ensheathing epineurium [Figure 1]. Proximally, the median and ulnar nerves were involved upto pronator quadrates and Guyon's canal, respectively, while distally there was involvement of digital branches of both the nerves [Figure 2]. Based on these characteristic imaging findings, the diagnosis of fibrolipomatous hamartoma (FLH) of the median and ulnar nerves was made.{Figure 1}{Figure 2}

An FLH is a benign, slowly growing tumor typically affecting the peripheral nerves. The median nerve is the most commonly reported nerve to be affected, however, ulnar, radial, axillary, and peroneal nerves are also affected.[1],[2]Simultaneous involvement of both median and ulnar nerves at the wrist is very rare. Toms et al.[3] in a study of 15 patients of FLH of upper limb reported single nerve (median or ulnar) involvement in 12 patients whereas three patients had multiple nerve involvement among which two patients had simultaneous involvement of brachial plexus and its branches, including the median, ulnar, radial, axillary, and musculocutaneous nerves.

MRI is the diagnostic modality of choice. It is a widely held view that characteristic MRI appearance establishes the diagnosis of FLH without the need for histological diagnosis.[3],[4] The characteristic appearance is likened to a “coaxial cable” which represents thickened axonal bundles separated by the interspersed fat, together ensheathed in thick epineurium.[3],[4]

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