Neurol India Close
 

Figure 1: IDH1-R132H suppresses proliferation, migration, invasion and increases apoptosis in glioblastoma cells.(a) Protein expression of IDH1 and IDH1-R132H in U87 and U251 cells transfected with IDH1-WT or IDH1-R132H. (b) Proliferation of U87 cells transfected with IDH1-WT or IDH1-R132H. (c) Proliferation of U251 cells transfected with IDH1-WT or IDH1-R132H. (d) Apoptosis of U87 cells transfected with IDH1-WT or IDH1-R132H. (e) Apoptosis of U251 cells transfected with IDH1-WT or IDH1-R132H. (f) Relative migration of U87 cells transfected with IDH1-WT or IDH1-R132H. (g) Relative migration of U251 cells transfected with IDH1-WT or IDH1-R132H. (h) Relative invasion of U87 cells transfected with IDH1-WT or IDH1-R132H. (i) Relative invasion of U251 cells transfected with IDH1-WT or IDH1-R132H. * P < 0.05; ** P < 0.01

Figure 1: IDH1-R132H suppresses proliferation, migration, invasion and increases apoptosis in glioblastoma cells.(a) Protein expression of IDH1 and IDH1-R132H in U87 and U251 cells transfected with IDH1-WT or IDH1-R132H. (b) Proliferation of U87 cells transfected with IDH1-WT or IDH1-R132H. (c) Proliferation of U251 cells transfected with IDH1-WT or IDH1-R132H. (d) Apoptosis of U87 cells transfected with IDH1-WT or IDH1-R132H. (e) Apoptosis of U251 cells transfected with IDH1-WT or IDH1-R132H. (f) Relative migration of U87 cells transfected with IDH1-WT or IDH1-R132H. (g) Relative migration of U251 cells transfected with IDH1-WT or IDH1-R132H. (h) Relative invasion of U87 cells transfected with IDH1-WT or IDH1-R132H. (i) Relative invasion of U251 cells transfected with IDH1-WT or IDH1-R132H. * <i>P</i> < 0.05; ** <i>P</i> < 0.01