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Figure 2: Shows the histological features of CCA. The tumor cells contain perinuclear dense Crooke's hyaline inclusion, (a) which are diffusely positive for pan CK. (b) and variably express CK7. (c) ACTH-positive granules are pushed to the periphery. (d) Original magnification ×160. CK = cytokeratin, CCA = Crooke's cell adenomas, ACTH = Adrenocorticotropic hormone

Figure 2: Shows the histological features of CCA. The tumor cells contain perinuclear dense Crooke's hyaline inclusion, (a) which are diffusely positive for pan CK. (b) and variably express CK7. (c) ACTH-positive granules are pushed to the periphery. (d) Original magnification ×160. CK = cytokeratin, CCA = Crooke's cell adenomas, ACTH = Adrenocorticotropic hormone