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Figure 2: The permeability and perfusion parameters of MS lesions and NAWM regions. (a) Ktrans map, (b) Kep map, (c) Ve map, (d) Vp map. (e) CBF map, (f) CBV map. ROI 1 located in CE lesions (Polygon), ROI 2 located in the NAWM regions close to the lesions (Rectangle), ROI 3 located in the NAWM regions far from the lesions (Circle)

Figure 2: The permeability and perfusion parameters of MS lesions and NAWM regions. (a) K<sup>trans</sup> map, (b) Kep map, (c) Ve map, (d) Vp map. (e) CBF map, (f) CBV map. ROI 1 located in CE lesions (Polygon), ROI 2 located in the NAWM regions close to the lesions (Rectangle), ROI 3 located in the NAWM regions far from the lesions (Circle)