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Figure 1: Photomicrographs representative of glioblastoma-NOS (a: Hematoxylin and eosin [HE] x100), gliosarcoma (b: HE x100), immunohistochemistry positive for IDH1R132H mutation (c: IHCx100), immunohistochemistry positive for p53 protein (d: IHCx100), immunohistochemistry for ATRX protein (e: IHCx100 – retained protein, f: IHCx200 – loss of protein), EGFR FISH (g and h: FISH; g: amplified, h:non-amplified)

Figure 1: Photomicrographs representative of glioblastoma-NOS (a: Hematoxylin and eosin [HE] x100), gliosarcoma (b: HE x100), immunohistochemistry positive for IDH1R132H mutation (c: IHCx100), immunohistochemistry positive for p53 protein (d: IHCx100), immunohistochemistry for ATRX protein (e: IHCx100 – retained protein, f: IHCx200 – loss of protein), EGFR FISH (g and h: FISH; g: amplified, h:non-amplified)