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Figure 4: Focal cortical dysplasia Type IIB. Large dysmorphic neurons with markedly enlarged cell body with dispersed Nissl substance (a) and accumulation of phosphorylated neurofilaments displacing nucleus to the periphery of cytoplasm (b). Several balloon cells are seen with a large cell body and opaque glassy eosinophilic cytoplasm (c) accumulating glial fibrillary acidic protein (GFAP) within the cytoplasm (d)

Figure 4: Focal cortical dysplasia Type IIB. Large dysmorphic neurons with markedly enlarged cell body with dispersed Nissl substance (a) and accumulation of phosphorylated neurofilaments displacing nucleus to the periphery of cytoplasm (b). Several balloon cells are seen with a large cell body and opaque glassy eosinophilic cytoplasm (c) accumulating glial fibrillary acidic protein (GFAP) within the cytoplasm (d)