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Figure 2: (a) A case of secondary glioblastoma (Hematoxylin and eosin [H and E]) with positive IDH1 IHC and loss of ATRX expression (insets). PCR sequence shows the IDH1R132H mutation. (b) A case of anaplastic oligodendroglioma (H and E) with negative IDH1 IHC and normal ATRX expression (insets). PCR sequence shows the IDH2R172K mutation

Figure 2: (a) A case of secondary glioblastoma (Hematoxylin and eosin [H and E]) with positive IDH1 IHC and loss of ATRX expression (insets). PCR sequence shows the IDH1R132H mutation. (b) A case of anaplastic oligodendroglioma (H and E) with negative IDH1 IHC and normal ATRX expression (insets). PCR sequence shows the IDH2R172K mutation