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Figure 1: Sagittal T1 (a), axial T1 (b), and axial T2 (c, d) sections of MRI brain showing “Z”-shaped or kinked brainstem (white arrow) which is hypoplastic, has partial midline cleft with asymmetrical focal bulges involving left hemipons (black arrow), small and dysplastic cerebellum (white block arrow), fused basal ganglia structures with dysgenesis of anterior limbs of internal capsules (“absent/dysgenetic ALIC sign,” white arrowheads), diffuse bilateral perisylvian polymicrogyria (black block arrows) and hypoplastic corpus callosum (asterisk). Imaging findings are suggestive of tubulinopathy

Figure 1: Sagittal T1 (a), axial T1 (b), and axial T2 (c, d) sections of MRI brain showing “Z”-shaped or kinked brainstem (white arrow) which is hypoplastic, has partial midline cleft with asymmetrical focal bulges involving left hemipons (black arrow), small and dysplastic cerebellum (white block arrow), fused basal ganglia structures with dysgenesis of anterior limbs of internal capsules (“absent/dysgenetic ALIC sign,” white arrowheads), diffuse bilateral perisylvian polymicrogyria (black block arrows) and hypoplastic corpus callosum (asterisk). Imaging findings are suggestive of tubulinopathy